The project foresees the development of a base ready for oral use, mucoadhesive, able to solubilize Budesonide; this anti-inflammatory active ingredient has shown greater clinical efficacy for the treatment of eosinophilic esophagitis, a disease now considered rare, with a prevalent pediatric incidence.
The Wagner base is able to solubilize Budesonide (up to 8 mg/10 mL), increasing its bioavailability. It contains excipients that give it mucoadhesive properties and good palatability, increasing patient compliance.
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